| 1987 | Started scientific software business |
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| 1997 | Started sales of Chemical Computing Group Inc. (CCG) products |
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| 1998 | Started sales of SCM products |
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| Started sales of Gaussian Inc. products |
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| 1999 | Started sales of SciCo (now Materials Design, Inc) products |
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| 2001 | Started sales of COSMOlogic GmbH & Co. KG productgs. |
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| Started sales of AEON Technology Inc. producrts |
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| 2002 | Started sales of ChemInnovation Software, Inc. products |
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| Started sales of CCG products to far east countries. |
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| 2005 | Started sales of Daylight Chemical Information Systems, Inc. products. |
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| Started sales of Reaction Design (now part of ANSYS, Inc.) products. |
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| Started sales of Partek Inc. products. |
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| 2006 | Started sales of Scienomics products |
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| 2007 | Started sales of Stewart Computational Chemistry products |
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| Started sales of BioSolveIT GmbH products |
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| 2009 | Started sales of Culgi B.V. products |
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| 2010 | Started sales of CimplSoft products |
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| 2013 | Started sales of Prous Institute for Biomedical Research S.A. products |
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| 2014 | Started sales of NEBION AG products |
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| 2015 | Started sales of Collaborative Drug Discovery, Inc. products |
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| Started sales of Dotmatics Ltd. products to government and academic customers. |
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| 2016 | Started sales of Scilligence Corporation products |
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| Started sales of Bioinfogate S.L. products |
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